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Liff wrote:First off, I rate this thread as good. Among people who deal with antibacterials or antibiotics as part of their normal job there is consensus that there is not a "The One" antibiotic, and no one should be looking for something like that. Anytime a good question is asked and there is that much consensus, it clearly represents the current thought in the state of whatever topic is being discussed.
There are good romper stomper combinations that fail in a different infection, and the better point is that the reverse is also true. And we have not even started to discuss why an E Coli infection of the prostate needs cipro for 28 days while the same E Coli bacteria causing a UTI needs therapy for 3 days. (Guidelines vary.) Or how different areas in this country have different rates of antibacterial resistance. What works well in Texas may be a poor choice in North Dakota.
Lots and lots goes into this topic. A little knowledge can be (not "is", but "can be") a dangerous thing.
Either way, stock up of fish antibiotics. (Just in case: blue text means sarcasm on this board.)



Tperkins wrote:Edit: Liff, out of curioisity, why the sarcasm on the fish antibiotics? Their use is not contraindicated as long as you know what you're doing, or are you assuming their use by the general and uneducated (pharmaceutically, no insults intended) public?


Liff wrote:Tperkins wrote:Edit: Liff, out of curioisity, why the sarcasm on the fish antibiotics? Their use is not contraindicated as long as you know what you're doing, or are you assuming their use by the general and uneducated (pharmaceutically, no insults intended) public?
Two reasons. The first is that while the use antibiotics is not contraindicated, it is also not indicated. We all know it is probably the same everything that is sold indicated for human use, but fish antibiotics are not indicated for human use.
The second is that the people who advocate fish antibiotics, especially storing them for the paw, do not have a water filter, soap, any idea how antibacterials work in the first place, any idea as to how long or how much to take, have no idea that about half of all ER admits for adverse drug reactions are due to antibacterials, and they generally think the PDR is a great reference source. I don't care if they hurt themselves, but it is a different story when one person's actions hurt another person.
Antibiotics are not the be all end all that people think they are. Here is a good link, 80,000 Chinese die from using antibiotics every single year. Not die from the infection, but die from using the antibiotics.
YMMV and all, but don't let your preps hurt or kill you.


PotatoMuncher wrote:Z-Pack, straight up. Very commonly used, very easy for even the most average Joe to follow, and it's a good almost-cure-all.
PotatoMuncher wrote:Z-Pack, straight up. Very commonly used, very easy for even the most average Joe to follow, and it's a good almost-cure-all.
Krustofski wrote:Dude, you're an open system which has energy pumped into it at least once a day. Entropy doesn't stand a chance. Plus, all living things are thermodynamically unstable anyway, we're held together by pure kinetics. You're not special. Um... what I'm trying to say is: Happy Birthday.

duodecima wrote:PotatoMuncher wrote:Z-Pack, straight up. Very commonly used, very easy for even the most average Joe to follow, and it's a good almost-cure-all.
Until, since the PAW is unlikely to happen tommorrow, it gets so overused that the resistance rates go up. I get more requests for this antibiotic than any other, from people who just know that their personal respiratory infection really needs it. Because "I've had so much amoxicillin I'm immune to it now." Maybe everybody else has a virus, but no, they need azithromycin. Levaquin used to have really low resistance rates too, no longer the case... I am equally if not more frustrated with my colleagues who collude in this practice, rather than pissing off an admittedly ill and uncomfortable patient by explaining them that an antibiotic won't help...
It doesn't work for most urinary or abdominal infections, btw. Far from first choice for wound/skin, as well.
[/rant]
Azithro is still a very nice drug, it's still probably my #2 prescribed antibiotic, when antibiotics are indicated. Good choice for many things respiratory.
Antibiotic misuse and overuse, by professionals and patients, is a personal pet peeve of mine. (in case you hadn't noticed.) (fake edit : waves hello to dallas)
Also, I'm not blowing anyone for vanc or zosyn unless I've also got sterile IV stuff available.

duodecima wrote:PotatoMuncher wrote:Z-Pack, straight up. Very commonly used, very easy for even the most average Joe to follow, and it's a good almost-cure-all.
Until, since the PAW is unlikely to happen tommorrow, it gets so overused that the resistance rates go up. I get more requests for this antibiotic than any other, from people who just know that their personal respiratory infection really needs it. Because "I've had so much amoxicillin I'm immune to it now." Maybe everybody else has a virus, but no, they need azithromycin. Levaquin used to have really low resistance rates too, no longer the case... I am equally if not more frustrated with my colleagues who collude in this practice, rather than pissing off an admittedly ill and uncomfortable patient by explaining them that an antibiotic won't help...
It doesn't work for most urinary or abdominal infections, btw. Far from first choice for wound/skin, as well.
[/rant]
Azithro is still a very nice drug, it's still probably my #2 prescribed antibiotic, when antibiotics are indicated. Good choice for many things respiratory.
Antibiotic misuse and overuse, by professionals and patients, is a personal pet peeve of mine. (in case you hadn't noticed.) (fake edit : waves hello to dallas)
Also, I'm not blowing anyone for vanc or zosyn unless I've also got sterile IV stuff available.
SRO1911 wrote:- I have "several" vials of rocephin, along with the requisite lidocain and saline solution to reconstitute. As well as the proper accompaniment of prednisone.
Knowing how bad that shit HURTS going in, there is not much risk of abuse.
Krustofski wrote:Dude, you're an open system which has energy pumped into it at least once a day. Entropy doesn't stand a chance. Plus, all living things are thermodynamically unstable anyway, we're held together by pure kinetics. You're not special. Um... what I'm trying to say is: Happy Birthday.

SRO1911 wrote:My meds are about my most successful prep. Aside from enough Imitrex to drown a bus load of zeds I have managed to stock up on the best anti-biotics for me. With a massively deviated septum I get a lot of sinus infections and have a very good dr. - I have "several" vials of rocephin, along with the requisite lidocain and saline solution to reconstitute. As well as the proper accompaniment of prednisone.
Knowing how bad that shit HURTS going in, there is not much risk of abuse.
I have proper dosages for every one in my family charted in the med bag - if you are not part of my planned group you are SOL.
duodecima wrote:SRO1911 wrote:- I have "several" vials of rocephin, along with the requisite lidocain and saline solution to reconstitute. As well as the proper accompaniment of prednisone.
Knowing how bad that shit HURTS going in, there is not much risk of abuse.
The big problem with antibiotic misuse is that, it's not done recreationally, or willfully - it's done in the completely sincere albeit incorrect belief that the provider and/or patient are doing the right and appropriate thing to get better. nobody abuses antibiotics like they're narcotics or anything.
I realize most folks here a prepping for a PAW and not planning to use this stuff until then, unless their provider tells them to do so. Some folks, as above, have specific knowledge and direction about when to use things for their situation.
But that's another reason why the whole fish antibiotics thing, or the idea that any antibiotic could be anything remotely like a 'cure-all' makes a some of us grind the enamel off our teeth.
dallas wrote:duodecima wrote:SRO1911 wrote:- I have "several" vials of rocephin, along with the requisite lidocain and saline solution to reconstitute. As well as the proper accompaniment of prednisone.
Knowing how bad that shit HURTS going in, there is not much risk of abuse.
The big problem with antibiotic misuse is that, it's not done recreationally, or willfully - it's done in the completely sincere albeit incorrect belief that the provider and/or patient are doing the right and appropriate thing to get better. nobody abuses antibiotics like they're narcotics or anything.
I realize most folks here a prepping for a PAW and not planning to use this stuff until then, unless their provider tells them to do so. Some folks, as above, have specific knowledge and direction about when to use things for their situation.
But that's another reason why the whole fish antibiotics thing, or the idea that any antibiotic could be anything remotely like a 'cure-all' makes a some of us grind the enamel off our teeth.
I think I just cracked a molar.

Tperkins wrote:dallas wrote:duodecima wrote:SRO1911 wrote:- I have "several" vials of rocephin, along with the requisite lidocain and saline solution to reconstitute. As well as the proper accompaniment of prednisone.
Knowing how bad that shit HURTS going in, there is not much risk of abuse.
The big problem with antibiotic misuse is that, it's not done recreationally, or willfully - it's done in the completely sincere albeit incorrect belief that the provider and/or patient are doing the right and appropriate thing to get better. nobody abuses antibiotics like they're narcotics or anything.
I realize most folks here a prepping for a PAW and not planning to use this stuff until then, unless their provider tells them to do so. Some folks, as above, have specific knowledge and direction about when to use things for their situation.
But that's another reason why the whole fish antibiotics thing, or the idea that any antibiotic could be anything remotely like a 'cure-all' makes a some of us grind the enamel off our teeth.
I think I just cracked a molar.
Wouldn't want that to get infected; maybe take some antibiotics?Just kidding.
Anyway, on those IDSA guidelines, I agree with everything there except I'm suprised they say that antihistamines and decongestants are contraindicated for a sinus infection? While steriods can help, I've often seen/heard them contraindicated due to possible addiction. I've always taken 120mg of Pseudoephedrine for nasal congestion, and add Guaifenesin if I'm getting chest congestion; I've certainly noticed an improvement in both, certainly not a deterioration. YMMV I suppose? Just thought that was kind of odd.
dallas wrote:Tperkins wrote:dallas wrote:duodecima wrote:
The big problem with antibiotic misuse is that, it's not done recreationally, or willfully - it's done in the completely sincere albeit incorrect belief that the provider and/or patient are doing the right and appropriate thing to get better. nobody abuses antibiotics like they're narcotics or anything.
I realize most folks here a prepping for a PAW and not planning to use this stuff until then, unless their provider tells them to do so. Some folks, as above, have specific knowledge and direction about when to use things for their situation.
But that's another reason why the whole fish antibiotics thing, or the idea that any antibiotic could be anything remotely like a 'cure-all' makes a some of us grind the enamel off our teeth.
I think I just cracked a molar.
Wouldn't want that to get infected; maybe take some antibiotics?Just kidding.
Anyway, on those IDSA guidelines, I agree with everything there except I'm suprised they say that antihistamines and decongestants are contraindicated for a sinus infection? While steriods can help, I've often seen/heard them contraindicated due to possible addiction. I've always taken 120mg of Pseudoephedrine for nasal congestion, and add Guaifenesin if I'm getting chest congestion; I've certainly noticed an improvement in both, certainly not a deterioration. YMMV I suppose? Just thought that was kind of odd.
That is the "fun" thing about medicine. There are few absolutes. There are exceptions to about everything. Psuedophedrine can open the nasal passages, but the reduction in bloodflow can increase the risk or severity of a bacterial infection. It does not happen to everyone or probably even to a lot of the patients, but the risk is there.
I have to continually change what I do. The learning is ever ending.

dallas wrote:Vicarious_Lee wrote:First pick is Levaquin. Broad-Spectrum, excellent bioavailability, and even gets into abscesses somewhat. Next is metronidazole, for reasons Liff said.
In fact, that combination taken orally would be pretty romper stomper on nearly anything.
Would it be your pick for MRSA? Where I work, all soft tissue infections are presumed to be MRSA.


duodecima wrote:PotatoMuncher wrote:Z-Pack, straight up. Very commonly used, very easy for even the most average Joe to follow, and it's a good almost-cure-all.
I am equally if not more frustrated with my colleagues who collude in this practice, rather than pissing off an admittedly ill and uncomfortable patient by explaining them that an antibiotic won't help...
It doesn't work for most urinary or abdominal infections, btw. Far from first choice for wound/skin, as well.
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